Extended coasting duration exerts a negative impact on IVF cycle outcome due to premature luteinization

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A high response to controlled ovarian stimulation induces premature luteinization with a negative impact on pregnancy outcomes in a gonadotropin-releasing hormone antagonist cycle

OBJECTIVE The goal of this study was to investigate the relationship between serum progesterone (P4) levels on the day of human chorionic gonadotropin (hCG) administration and the pregnancy rate among women undergoing controlled ovarian stimulation for in vitro fertilization (IVF) or intracytoplasmic sperm injection-embryo transfer (ICSI-ET) using a flexible antagonist protocol. METHODS This ...

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I-28: The Effect of Coasting Duration on Oocytes Retrieved in ART Cycle

Background: Coasting is one of the most common strategies which has been proposed for preventing ovarian hyperstimulation (OHSS) in overstimulated cycles. However, the debate on the effect of coasting duration (days) on ART cycles outcome is ongoing. This study aimed to assess the influence of coasting duration in oocytes number and quality and fertilization rate in patients with male factor in...

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Premature Progesterone Elevation Does Not Affect Pregnancy Outcome in High-Responder Patients Undergoing Short-Interval Coasting in IVF Cycles

BACKGROUND We aimed to present the relationship between premature progesterone elevation (PPE) and clinical outcomes in high-responder patients who had a coasting period of <4 days in length due to their high risk of developing ovarian hyperstimulation syndrome (OHSS) and who were treated with a long-acting gonadotropin-releasing hormone agonist (GnRH-agonist) protocol in in vitro fertilization...

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The Eeffect of Coasting on Intracytoplasmic Sperm Injection Outcome in Antagonist and Agonist Cycle

Objective Coasting can reduce the ovarian hyperstimulation syndrome (OHSS) risk in ovulation induction cycles before intracytoplasmic sperm injection (ICSI). This study aimed to investigate the effect of gonadotropin-releasing hormone (GnRH) agonist and GnRH antagonist protocols to controlled ovarian hyperstimulation (COH) cycles with coasting on the parameters of ICSI cycles and the outcome. M...

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With low ovarian reserve, Highly Individualized Egg Retrieval (HIER) improves IVF results by avoiding premature luteinization

BACKGROUND Highly Individualized Egg Retrieval (HIER), defined as age-specific early oocyte retrieval (ER), has been demonstrated to avoid premature luteinization in women ≥43. We here investigated whether HIER also applies to younger women with premature ovarian aging (POA), and what best lead follicle size should be for administration of ovulation-triggers. METHODS Fifty-six women ≥43, and ...

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ژورنال

عنوان ژورنال: Reproductive BioMedicine Online

سال: 2004

ISSN: 1472-6483

DOI: 10.1016/s1472-6483(10)61633-1